IOF Positions and Statements

child receiving an insulin shot
Despite an up to six-fold increased risk of broken bones in patients with type 1 diabetes mellitus (T1DM), the relationship between diabetes and osteoporosis has, until recently, suffered from a general lack of attention and research. As a result, health professionals who treat diabetic patients often do not recognize that fragility fractures are a major complication of the disease. Read more
A retired couple enjoy a wholesome breakfast filled with calcium.
IOF is concerned that recent media reports may be giving the false impression that calcium is not essential to good bone health, and are thus causing confusion among the general public as well as osteoporosis patients. Here are some facts to keep in mind: Read more
senior man sitting on bench in the park
The International Osteoporosis Foundation (IOF) today issued a statement in response to an article published on May 26 in the BMJ1, which we deem inaccurate and misleading on a number of levels. Some of the authors’ key misconceptions are addressed below, particularly in relation to their main conclusion that “The dominant approach to hip fracture prevention is neither viable as a public health... Read more
A new study by an International Osteoporosis Foundation (IOF) and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) scientific working group summarizes the clinical performance of serum procollagen type I N propeptide (s-PINP) and serum C-terminal cross-linking telopeptide of type I collagen (s-CTX) in fracture risk prediction in untreated individuals in prospective... Read more
One of the most important advances in osteoporosis management of the past decade has been the advent of fracture risk assessment algorithms. Today, rather than relying on bone mineral density values alone, doctors use tools such as FRAX, a widely available calculator (, to help identify patients in need of treatment. Read more
This statement is in response to a recent report published in the Lancet which has implied that vitamin D does not prevent osteoporosis, defined as low bone mineral density (BMD), in healthy middle-aged people (1). The authors found that vitamin D had no net effect on BMD at the spine but that it did significantly increase femoral neck BMD. Read more
A new systematic review published in the British Journal of Nutrition*, is one of the first to focus on patterns of vitamin D status worldwide and in key population subgroups, using continuous values for 25(OH)D to improve comparisons. Read more
Distal radius fractures (often simply termed wrist or Colles' fractures) are the second most common fractures in the elderly. Beyond the immediate impact on the patient, wrist fractures in older adults often indicate underlying osteoporosis and high risk of subsequent fragility fractures. Read more
The International Osteoporosis Foundation (IOF) has endorsed a global consensus statement on menopausal hormone therapy (MHT) published today in the journals Climacteric and Maturitas. Read more
The International Osteoporosis Foundation (IOF) concurs with the United States Preventive Services Task Force (USPSTF)1 which has stated that daily supplementation with doses of vitamin D ≤ 400 IU and calcium ≤ 1,000 mg has no net benefit for the primary prevention of fractures in non-institutionalized asymptomatic adults without previous history of fractures. Read more


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