Bone Imaging Working Group

Members

Co-Chairs: Dr Mary Bouxsein and Professor Harry Genant
Members: Claude Arnaud, Mary Bouxsein (co-chair), Daniel Chappard, Roland Chapurlat, Juliet Compston, Adolfo Diez-Perez, Jean-Pierre Devogelaer, Hans Peter Dimai,  Dieter Felsenberg, Harry Genant (co-chair), Claus C. Glüer, Sarath Lekamwasam, Paul Miller, Osvaldo Daniel Messina, Nick Pocock, Philip Sambrook
Externally co-opted members: Judith Adams, Neil Binkley, Leon Lenchik, Christian Roux, John Schousboe, Pawel Szulc, Tamara Vokes

Vision

To explore surrogate endpoints for osteoporosis and fragility fracture.

Aim

The aim of the Bone Imaging Working Group is to define, facilitate and enable the use of bone imaging/biomechanical markers as surrogate endpoints for osteoporosis clinical trials and eventually to expand their application to clinical practice as valid measures of disease status and response to therapy.

Objectives

  • Highlight the current status (performance and limitations) of non-invasive imaging techniques for assessing bone quality
  • Evaluate the ability of imaging techniques in detecting patients with fractures, at high risk of fracture and in monitoring changes in bone quality after pharmacological treatment
  • Elaborate educational tools that would orientate scientists and health professionals towards research priorities

Projects

Vertebral Fracture Initiative 2: exploring the indication for DXA-based vertebral fracture assessment

The Vertebral Fracture Initiative was created to encourage radiologists to detect vertebral fractures on radiographs, to report them clearly as fractures, and to recommend appropriate investigation and management.

A recent update of these resources and teaching slides included up-to-date studies and a larger section on DXA-based Vertebral Fracture Assessment (VFA) (its concept, clinical performance, advantages, limitations and some image cases). Because the VFI2 emphasizes DXA-based VFA, the target audience extends to clinicians as well as radiologists.