Inadequate Responders Working Group

Members

Chair: A Diez Perez

Members: R. Adachi, D. Agnusdei, J. Compston, S. Cummings, A. Diez-Perez (Chair), R. Eastell, E .Eriksen, U. Liberman, E. Seeman
External advisor: Jesus Gonzalez-Macias

Aim

Defining inadequate response is very important in practical settings, for patients and clinicians and for the access and reimbursement of anti-osteoporotic drugs. However, many debatable points have been raised in defining which clinical signs constitute a non-response.

Objectives

The objective of the working group is to establish an IOF Position Paper on what constitutes an inadequate response to osteoporosis treatment, based on the operational definitions published recently in a 2008 article ‘Inadequate responders to osteoporosis treatment: proposal for an operational definition’, co-written by Dr J. Gonzales-Macias and A. Diez Perez in the journal Osteoporosis International.

Publication

Treatment failure in osteoporosis. Diez-Perez A, Adachi JD, Agnusdei D, et al. for the IOF CSA Inadequate Responders Working Group Osteoporosis International 2012, December 2012, Volume 23, Issue 12, pp 2769-2774 DOI: 10.1007/s00198-012-2093-8