IOF Positions and Statements

A new review published by a joint scientific working group of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) and the International Osteoporosis Foundation (IOF) finds that current evidence continues to support the potential for bone turnover markers (BTMs) to provide clinically useful information for monitoring osteoporosis treatment.1 The IFCC-IOF Working Group... Read more
The newly revised consensus statement serves to update and expand the areas of consensus following the publication of the Global Consensus on Menopausal Hormone Therapy (MHT) by leading global menopause societies in 2013. At the time, the Global Consensus succeeded in presenting guidelines that have been helpful to both healthcare providers and potential users of MHT. Read more
In people with osteoporosis, one fracture often leads to more fractures, and potentially a future of pain, disability, and poor quality of life. While studies have shown that such high-risk patients benefit from appropriate medication to reduce future fracture risk, more research is needed on the effect of osteoporosis medications on fracture healing.  Read more
senior and doctor checking ankle bandage
Una fractura en las personas con osteoporosis, a menudo, conduce a más fracturas. Los estudios han demostrado que estos pacientes de alto riesgo se benefician de los medicamentos apropiados para reducir el riesgo de fracturas futuras, sin embargo, se necesita más investigación sobre el efecto de los medicamentos para la osteoporosis en la consolidación de fracturas Read more
patient sits with doctor
A new editorial published by an International Osteoporosis Foundation (IOF) Working Group urges physicians to individualize treatment decisions based on their patient’s fracture risk, rather than automatically interrupting or stopping bisphosphonate therapy after five or three years. Read more
child receiving an insulin shot
Despite an up to six-fold increased risk of broken bones in patients with type 1 diabetes mellitus (T1DM), the relationship between diabetes and osteoporosis has, until recently, suffered from a general lack of attention and research. As a result, health professionals who treat diabetic patients often do not recognize that fragility fractures are a major complication of the disease. Read more
A retired couple enjoy a wholesome breakfast filled with calcium.
IOF is concerned that recent media reports may be giving the false impression that calcium is not essential to good bone health, and are thus causing confusion among the general public as well as osteoporosis patients. Here are some facts to keep in mind: Read more
senior man sitting on bench in the park
The International Osteoporosis Foundation (IOF) today issued a statement in response to an article published on May 26 in the BMJ1, which we deem inaccurate and misleading on a number of levels. Some of the authors’ key misconceptions are addressed below, particularly in relation to their main conclusion that “The dominant approach to hip fracture prevention is neither viable as a public health... Read more
A new study by an International Osteoporosis Foundation (IOF) and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) scientific working group summarizes the clinical performance of serum procollagen type I N propeptide (s-PINP) and serum C-terminal cross-linking telopeptide of type I collagen (s-CTX) in fracture risk prediction in untreated individuals in prospective... Read more
One of the most important advances in osteoporosis management of the past decade has been the advent of fracture risk assessment algorithms. Today, rather than relying on bone mineral density values alone, doctors use tools such as FRAX, a widely available calculator (, to help identify patients in need of treatment. Read more


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