IOF Positions and Statements

This statement is in response to a recent report published in the Lancet which has implied that vitamin D does not prevent osteoporosis, defined as low bone mineral density (BMD), in healthy middle-aged people (1). The authors found that vitamin D had no net effect on BMD at the spine but that it did significantly increase femoral neck BMD. Read more
A new systematic review published in the British Journal of Nutrition*, is one of the first to focus on patterns of vitamin D status worldwide and in key population subgroups, using continuous values for 25(OH)D to improve comparisons. Read more
Distal radius fractures (often simply termed wrist or Colles' fractures) are the second most common fractures in the elderly. Beyond the immediate impact on the patient, wrist fractures in older adults often indicate underlying osteoporosis and high risk of subsequent fragility fractures. Read more
The International Osteoporosis Foundation (IOF) has endorsed a global consensus statement on menopausal hormone therapy (MHT) published today in the journals Climacteric and Maturitas. Read more
The International Osteoporosis Foundation (IOF) concurs with the United States Preventive Services Task Force (USPSTF)1 which has stated that daily supplementation with doses of vitamin D ≤ 400 IU and calcium ≤ 1,000 mg has no net benefit for the primary prevention of fractures in non-institutionalized asymptomatic adults without previous history of fractures. Read more
Sarcopenia, or the gradual loss of muscle mass, is a common consequence of ageing, and poses a significant risk factor for disability in older adults. As muscle strength plays an important role in the tendency to fall, sarcopenia leads to an increased risk of fractures and other injuries. Read more
Much of the research defining osteoporosis and fracture risk has focused on older adults, i.e. postmenopausal women and men over the age of 50. While older adults areat highest risk of osteoporosis and related fractures, the disease can also affect younger adultsbetween 20 and 50 years of age. Read more
A solid body of evidence shows that calcium is an important mineral for bone health in people of all ages. In early life, calcium helps to build stronger and denser bones. In later life, it plays a critical role in reducing the risk for osteoporosis and fractures. Read more
Osteoporosis constitutes a major public health problem through its association with age-related fractures, most notably those of the hip. As life expectancy rises around the world, along with the number of elderly people in every geographic region, the incidence of hip fractures is estimated to reach 6.3 million in 2050 - assuming a constant age-specific rate of fracture in men and women. Read more
A new editorial published in  Annals of Clinical Biochemistry (2011; 48:91-92) byS. D. Vasikaran, C. Cooper and J. A. Kanis emphasizes the important messages of the recent IOF-IFCC Position paper on bone markers. Read more


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